The Dice Tower 2010 award nominees have just been released. It's a bit of a mixed bag in my mind. There are a few that will definitely get my vote while others I really want to try.
String railway and Dominant Species both sound really good, but its impossible to get a copy so I doubt I will get to try them some time soon.
Best game for me, 7 Wonders. I have played this game so many times and still enjoy it. As for the other categories, I need to think a bit more.